H2N2V1, Main, Exploration, bibRecord, 000635

Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents.

Identifieur interne : 000635 ( Main/Exploration ); précédent : 000634; suivant : 000636

Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents.

Auteurs : Hanane Elayadi [Maroc] ; Michael Smietana [France] ; Jean-Jacques Vasseur [France] ; Jan Balzarini [Belgique] ; Hassan B. Lazrek [Maroc]

Source :

Archiv der Pharmazie / Chemistry in Life Sciences [ 0365-6233 ] ; 2014-02-03.

RBID : Hal:hal-01004380

Abstract

Montmorillonite K10 impregnated with copper dichloride and potassium iodide (CuCl2/KI/K10) was used as catalyst in the cycloaddition of azides and propargylnucleobases, to provide the corresponding 1,4-disubstituted 1,2,3-triazoles in good yield. All compounds 16-23 were evaluated for their antiviral activity in vitro. Compound 18 showed moderate inhibition against influenza virus A (H3N2).

Url:

https://hal.archives-ouvertes.fr/hal-01004380

DOI: 10.1002/ardp.201300260

Affiliations:

Belgique, France, Maroc

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000281
to stream Hal, to step Curation: 000281
to stream Hal, to step Checkpoint: 000135
to stream Main, to step Merge: 000636
to stream Main, to step Curation: 000635

Le document en format XML

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<country name="Belgique"><noRegion><name sortKey="Balzarini, Jan" sort="Balzarini, Jan" uniqKey="Balzarini J" first="Jan" last="Balzarini">Jan Balzarini</name>
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   |texte=   Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents.
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Serveur d'exploration H2N2

Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents.

Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents.

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Abstract

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